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Features of diagnostics and treatment of multiple myeloma complicated by bone and extramedullar plazmacytoma

https://doi.org/10.24412/2311-5068-2023-11-1-73

Abstract

Two clinical observations of the diagnosis of bone and solitary plasmacytoma in patients with a non-secreting variant of multiple myeloma are presented. A patient with bone plasmacytoma achieved partial remission of the disease as a result of chemotherapy and was referred to a federal center for autologous stem cell transplantation. The patient with extramedullary plasmacytoma turned out to be resistant to chemotherapy and radiation therapy, and a lethal outcome was stated. A conclusion was made about the worst prognosis of multiple myeloma in the presence of extramedullary lesions.

About the Authors

A. A. Grigorenko
Amur Regional Oncological Dispensary; Amur State Medical Academy of the Ministry of Health of the Russian Federation
Russian Federation

Aleksej A. Grigorenko

Blagoveshchensk



V. V. Voitsekhovsky
Blagoveshchensk
Russian Federation

Valerij V. Voitsekhovsky

Blagoveshchensk



S. N. Roshchin
Amur Regional Oncological Dispensary
Russian Federation

Sergej N. Roshchin

Blagoveshchensk



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For citations:


Grigorenko A.A., Voitsekhovsky V.V., Roshchin S.N. Features of diagnostics and treatment of multiple myeloma complicated by bone and extramedullar plazmacytoma. Amur Medical Journal. 2023;11(1):73-80. (In Russ.) https://doi.org/10.24412/2311-5068-2023-11-1-73

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ISSN 2311-5068 (Print)