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Novel methods for studying therapeutic agents from adaptogenic raw materials under cold and heat exposure

https://doi.org/10.22448/AMJ.2025.1.20-24

EDN: ZXPZQJ

Abstract

A toxicological and hygienic assessment was conducted of a mixture composed of processed antler products and dihydroquercetin, aimed at enhancing organism resistance to low and high temperature conditions. It was established that this biologically active mixture possesses potent antioxidant and hepatoprotective properties and demonstrates high actoprotective activity under pathogenic exposure to environmental temperature factors. Furthermore, the mixture enhances the body’s adaptive capacity to both low and high temperatures.

About the Author

N. V. Korshunova
Amur State Medical Academy Ministry of Health of the Russian Federation
Russian Federation

Natalia V. Korshunova

Blagoveshchensk



References

1. Dorovskikh V.A., Tseluiko S.S. Antioxidant preparations of various chemical groups in the regulation of stressful effects. Blagoveshchensk: Amur GMA, 2004. 268 p. (In Russ.)

2. Dorovskikh V.A., Voronin N.I., Korshunova N.V. Kholod. Adaptation. Correction of changes. Blagoveshchensk: Amur GMA, 1998. 104 p. (In Russ.)

3. Dorovskikh V.A., Tseluiko S.S. Antioxidant preparations of various chemical groups in the regulation of stressful effects. Blagoveshchensk: AGMA, 2004. 268 p. (In Russ.)

4. Archakov A.I. Microsomal oxidation. Moscow: Nauka, 1975. 324 p. (In Russ.)

5. Kozyreva T.V. Adaptive changes in human temperature sensitivity in conditions of cold, heat and prolonged physical activity. Human Physiology. 2006. 32 (6): 103–108. (In Russ.)

6. Modern methods in biochemistry, edited by V.N. Orekhovich. Moscow: Medicine, 1977. 392 p. (In Russ.)

7. Krasovsky G.N., Zholdakova Z.I. Methodological guidelines for the development and scientific substantiation of maximum permissible concentrations of harmful substances in the water of reservoirs. Moscow, 1999. 75 p. (In Russ.)

8. Ivanova S.Z., Fedorova T.E., Ostroukhova L.A. et al. Polymer of dihydroquercetin from larch wood. Khimija Rastitel'nogo Syr'ja. 2001; 4: 21–24. (In Russ.)

9. Plotnikov M.V., Tyukavkina N.A., Plotnikova T.M. Medicines based on dicvertin. Tomsk: TSU, 2005. P. 228. (In Russ.).


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For citations:


Korshunova N.V. Novel methods for studying therapeutic agents from adaptogenic raw materials under cold and heat exposure. Amur Medical Journal. 2025;13(1):20-24. (In Russ.) https://doi.org/10.22448/AMJ.2025.1.20-24. EDN: ZXPZQJ

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ISSN 2311-5068 (Print)