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Preconception preparation and features of the course of pregnancy in women with progesterone deficiency

https://doi.org/10.24412/2311-5068-2023-11-1-16

Abstract

Menstrual disorders occupy the main place among gynecological diseases in girls of reproductive age. A low concentration of progesterone in the second phase of the cycle is one of the most common functional pathologies leading to impaired reproductive function. The purpose of the literature review: to study data on the features of preconception preparation and the course of pregnancy in women with progesterone deficiency. Insufficient hormonal support is accompanied by pathological secretory transformation of the endometrium, which prevents the formation of an «implantation window». When pregnancy occurs, there is a high risk of its complications: spontaneous miscarriage, placental disorders and preeclampsia. This category of women needs preconception preparation with timely diagnosis of luteal phase insufficiency (LPI) and additional dosing of gestagens in a cyclic mode.

About the Authors

I. N. Salko
Amur State Medical Academy of the Ministry of Health of the Russian Federation
Russian Federation

Irina N. Salko

Blagoveshchensk



D. S. Lysyak
Amur State Medical Academy of the Ministry of Health of the Russian Federation
Russian Federation

Denis S. Lysyak

Blagoveshchensk



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Salko I.N., Lysyak D.S. Preconception preparation and features of the course of pregnancy in women with progesterone deficiency. Amur Medical Journal. 2023;11(1):16-23. (In Russ.) https://doi.org/10.24412/2311-5068-2023-11-1-16

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ISSN 2311-5068 (Print)